Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075362 | 1.00 | TRPV4 (0.41) | TRPV4UTS2RHTR2AHTR2CPKM | |
| SCHEMBL5835283 | 0.81 | TRPV4 (0.50) | TRPV4UTS2RPKMTSHRPRKDC | |
| SCHEMBL31658274 | 0.81 | TRPV4 (0.50) | TRPV4UTS2RPKMTSHRPRKDC | |
| SCHEMBL5835086 | 0.80 | TRPV4 (0.46) | TRPV4UTS2RHTR2AHTR2CPKM | |
| SCHEMBL5745043 | 0.80 | TRPV4 (0.49) | TRPV4HTR2AHTR2CPKMTSHR | |
| SCHEMBL29679428 | 0.80 | TRPV4 (0.49) | TRPV4HTR2AHTR2CPKMTSHR | |
| SCHEMBL25381430 | 0.79 | TRPV4 (0.45) | TRPV4HTR2AHTR2CPKMTSHR | |
| SCHEMBL31036241 | 0.77 | GAA (0.51) | TRPV4PKMTSHRKDM4EALDH1A1 | |
| SCHEMBL21032455 | 0.74 | NOTUM (0.47) | TRPV4NOTUM | |
| SCHEMBL5240836 | 0.73 | TRPV4 (0.50) | TRPV4TSHRPRKDCKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177984-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |