SCHEMBL681973

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL877836	1.00	HCRTR1 (0.41)	HCRTR1HCRTR2CCR1FFAR4PDE4B
	SCHEMBL683342	0.91	PDE4B (0.42)	PDE4BPDE4APDE4DPDE4C
	SCHEMBL877637	0.91	PDE4B (0.42)	PDE4BPDE4APDE4DPDE4C
	SCHEMBL681978	0.87	HCRTR1 (0.40)	HCRTR1HCRTR2CCR1FFAR4PDE4B
	SCHEMBL878088	0.87	HCRTR1 (0.40)	HCRTR1HCRTR2CCR1FFAR4PDE4B
	SCHEMBL2137756	0.87	PDE4D (0.41)	PDE4BALDH1A1PDE4APDE4DPDE4C
	SCHEMBL682717	0.87	PDE4D (0.41)	PDE4BALDH1A1PDE4APDE4DPDE4C
	SCHEMBL2137866	0.85	NR1H2 (0.39)	CCR1PDE4B
	SCHEMBL682789	0.85	NR1H2 (0.39)	CCR1PDE4B
	SCHEMBL683355	0.85	NR1H2 (0.40)	CCR1ALDH1A1TRPC6ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.