Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.61 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.61 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | MGAM | O43451 | 4/20 | 0.55 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.55 |
| ▸ | SI | P14410 | 4/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814131 | 1.00 | CYP4Z1 (0.61) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL3544941 | 0.89 | EGLN3 (0.60) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL5793440 | 0.87 | ASAH1 (0.66) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL337266 | 0.87 | ASAH1 (0.66) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL535029 | 0.87 | ASAH1 (0.66) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL18206302 | 0.87 | ASAH1 (0.66) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL534984 | 0.87 | ASAH1 (0.66) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL535094 | 0.87 | ASAH1 (0.66) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL534899 | 0.87 | ASAH1 (0.66) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 | |
| SCHEMBL3252264 | 0.85 | HPGD (0.61) | CYP4Z1CYP1A2CYP2C8CYP2B6CYP4F8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938502-B1 | SELECTIVE ACYLATION METHOD | NOVO NORDISK AS (DK) | 2004-10-06 | — | — | EP | disclosed |
| EP-0938502-A1 | SELECTIVE ACYLATION METHOD | NOVO NORDISK A/S (DK) | 1999-09-01 | — | — | EP | disclosed |
| US-5905140-A | ACYLATING INSULIN, INSULIN ANALOGS, AND INSULIN PRECURSORS ON FREE EPSILON-AMINO GROUP OF LYSINE USING ACTIVATED AMIDE WITH ACYL GROUP IN POLAR SOLVENT IN PRESENCE OF BASE | NOVO NORDISK A/S, NOVO ALLE (DK) | 1999-05-18 | — | — | US | disclosed |
| WO-1998002460-A1 | SELECTIVE ACYLATION METHOD | NOVO NORDISK A/S (DK) | 1998-01-22 | — | — | WO | disclosed |