Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.49 |
| ▸ | DRD3 | P35462 | 10/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8864656 | 0.79 | DRD2 (0.62) | DRD2DRD3HTR1ADRD4DRD1 | |
| Hydrochloric Acid SCHEMBL8864132 | 0.79 | DRD2 (0.62) | DRD2DRD3HTR1ADRD4DRD1 | |
| Hydrochloric Acid SCHEMBL8864139 | 0.79 | DRD2 (0.62) | DRD2DRD3HTR1ADRD4DRD1 | |
| SCHEMBL6815931 | 0.78 | MAOB (0.40) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL6819914 | 0.78 | MAOB (0.40) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL23940685 | 0.78 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL20179482 | 0.78 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL10325099 | 0.78 | DRD2 (0.55) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL4459888 | 0.78 | DRD2 (0.55) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL10324560 | 0.78 | DRD2 (0.55) | DRD2DRD3HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041805-A1 | NEW PROCESS FOR THE PREPARATION OF RACEMIC ([2S[2R*[R[R*]]]] and ([2R[2S*[S[S*]]]]-(±)- α,α' -[imino-bis(methylene)]bis[6-fluorochroman-2-methanol] AND ITS PURE [2S[2R*[R[R*]& | EGIS Gyógyszergyár Rt. (HU) | 2004-05-21 | — | — | WO | disclosed |