Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.49 |
| ▸ | DRD3 | P35462 | 10/20 | 0.49 |
| ▸ | DRD4 | P21917 | 9/20 | 0.49 |
| ▸ | DRD1 | P21728 | 2/20 | 0.49 |
| ▸ | DRD5 | P21918 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23940685 | 1.00 | DRD2 (0.49) | DRD2DRD3DRD4DRD1DRD5 | |
| Hydrochloric Acid SCHEMBL8864656 | 0.87 | DRD2 (0.62) | DRD2DRD3DRD4DRD1DRD5 | |
| Hydrochloric Acid SCHEMBL8864139 | 0.87 | DRD2 (0.62) | DRD2DRD3DRD4DRD1DRD5 | |
| Hydrochloric Acid SCHEMBL8864132 | 0.87 | DRD2 (0.62) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL23940707 | 0.79 | DRD2 (0.65) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL14676000 | 0.79 | DRD2 (0.48) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL14676188 | 0.79 | DRD2 (0.48) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL6819900 | 0.78 | DRD2 (0.49) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL20007096 | 0.78 | DRD2 (0.46) | DRD2DRD3HTR1AMLNRADRB2 | |
| SCHEMBL23940671 | 0.76 | HTR1A (0.78) | DRD2DRD3HTR1AMLNRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141926-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141926-A1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | CYP4A11, CYP11B2, ADRB1 | DRD2 205/4885DRD3 237/4885DRD4 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.