Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488078 | 1.00 | AR (0.46) | ARCNR2F2RL1ALOX5CA3 | |
| SCHEMBL6819997 | 1.00 | AR (0.46) | ARCNR2F2RL1ALOX5CA3 | |
| SCHEMBL2046339 | 0.83 | CA3 (0.46) | ARCNR2F2RL1ALOX5CA3 | |
| SCHEMBL2046337 | 0.83 | CA3 (0.46) | ARCNR2F2RL1ALOX5CA3 | |
| SCHEMBL27817024 | 0.83 | AR (0.45) | ARCA3CA6CA5ACA9 | |
| SCHEMBL9048974 | 0.81 | ERN1 (0.40) | CNR2ALOX5ALDH1A1MAPTMEN1 | |
| SCHEMBL9048969 | 0.81 | ERN1 (0.40) | CNR2ALOX5ALDH1A1MAPTMEN1 | |
| SCHEMBL1404883 | 0.79 | MAPT (0.59) | ARMAOBALDH1A1MAPTKDM4E | |
| SCHEMBL1404884 | 0.79 | MAPT (0.59) | ARMAOBALDH1A1MAPTKDM4E | |
| SCHEMBL69993 | 0.78 | ALDH1A1 (0.55) | CNR2ALOX5ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041805-A1 | NEW PROCESS FOR THE PREPARATION OF RACEMIC ([2S[2R*[R[R*]]]] and ([2R[2S*[S[S*]]]]-(±)- α,α' -[imino-bis(methylene)]bis[6-fluorochroman-2-methanol] AND ITS PURE [2S[2R*[R[R*]& | EGIS Gyógyszergyár Rt. (HU) | 2004-05-21 | — | — | WO | disclosed |