Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820308 | 0.86 | GAA (0.57) | POLBMAPTKMT2AMEN1TP53 | |
| SCHEMBL14578751 | 0.85 | POLB (0.85) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL28997137 | 0.84 | POLB (0.62) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL6462546 | 0.82 | HDAC3 (0.58) | POLBHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6820154 | 0.82 | ALDH1A1 (0.60) | POLBMAPTKMT2AMEN1NPC1 | |
| SCHEMBL8582253 | 0.81 | L3MBTL1 (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL1107145 | 0.81 | MAPT (0.74) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL517697 | 0.81 | HDAC3 (0.86) | POLBHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL10441109 | 0.81 | CYP1A2 (0.54) | POLBMAPTALDH1A1 | |
| SCHEMBL5685344 | 0.81 | NPC1 (0.46) | POLBMAPTKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | disclosed |