Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820533 | 0.95 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL19994399 | 0.81 | SMN1; SMN2 (0.65) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4099160 | 0.80 | PDE5A (0.58) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6824163 | 0.79 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL13681845 | 0.79 | CNR1 (0.54) | SMN1; SMN2ALDH1A1MAPTMAPK1TP53 | |
| SCHEMBL7924468 | 0.78 | POLB (0.58) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1846537 | 0.77 | CYP1A2 (0.68) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6820421 | 0.77 | CYP1A2 (0.51) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6821316 | 0.75 | HDAC1 (0.35) | SMN1; SMN2POLBALDH1A1MAPTMAPK1 | |
| SCHEMBL6821585 | 0.74 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052872-A1 | HALOALKENE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-06-24 | — | — | WO | disclosed |