Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846537 | 0.90 | CYP1A2 (0.68) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL19994399 | 0.89 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL13681845 | 0.86 | CNR1 (0.54) | PDE5ASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL7924468 | 0.85 | POLB (0.58) | PDE5ASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL6820421 | 0.84 | CYP1A2 (0.51) | PDE5ASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL4097866 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1MAPTPOLBTSHR | |
| SCHEMBL20935220 | 0.82 | PDE5A (0.66) | PDE5ASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9836846 | 0.81 | PDE5A (0.64) | PDE5ASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL6824163 | 0.80 | SMN1; SMN2 (0.52) | PDE5ASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL6820510 | 0.80 | NPC1 (0.51) | SMN1; SMN2ALDH1A1MAPTPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2484342-A1 | Hair resiliency / body improver and hair cosmetic | Shiseido Company, Limited (JP) | 2012-08-08 | — | — | EP | disclosed |
| CN-101953755-B | Hair springiness and stiffness improving agent and hair cosmetic | SHISEIDO CO LTD | 2012-03-28 | — | — | CN | disclosed |
| CN-101953755-A | The tension force of hair and toughness improving agent and hair-dressing cosmetics | SHISEIDO CO LTD | 2011-01-26 | — | — | CN | disclosed |
| US-20090233975-A1 | Hair resiliency/body improver and hair cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| CN-101232863-A | Agent for improving hair tension and toughness and cosmetic for hair | SHISEIDO CO LTD (JP) | 2008-07-30 | — | — | CN | disclosed |
| EP-1911750-A1 | AGENT FOR IMPROVEMENT IN BOUNCE/BODY OF HAIR, AND HAIR COSMETIC | Shiseido Company, Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233975-A1 | Hair resiliency/body improver and hair cosmetic | MC1R, PNISR, HCRTR1 | PDE5A 1885/4885SMN1; SMN2 3823/4885CYP1A2 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.