Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820330 | 0.87 | SLC2A1 (0.52) | IDO1ALDH1A1STS | |
| SCHEMBL31191746 | 0.87 | SLC2A1 (0.52) | IDO1ALDH1A1STS | |
| SCHEMBL4914447 | 0.81 | GPR119 (0.53) | GPR119USP30ALDH1A1NPC1MAPT | |
| SCHEMBL13991764 | 0.81 | GPR119 (0.53) | GPR119USP30ALDH1A1NPC1MAPT | |
| SCHEMBL22467690 | 0.80 | KDM4E (0.55) | GPR119USP30ALDH1A1NPC1MAPT | |
| SCHEMBL21074855 | 0.80 | KDM4E (0.55) | GPR119USP30ALDH1A1NPC1MAPT | |
| SCHEMBL6498471 | 0.80 | KDM4E (0.55) | GPR119USP30ALDH1A1NPC1MAPT | |
| SCHEMBL29862513 | 0.79 | ALDH1A1 (0.52) | IDO1GPR119USP30ALDH1A1NPC1 | |
| SCHEMBL1880284 | 0.79 | ALDH1A1 (0.52) | IDO1GPR119USP30ALDH1A1NPC1 | |
| SCHEMBL13991761 | 0.79 | USP30 (0.46) | IDO1GPR119USP30ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032856-A2 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-04-22 | — | — | WO | disclosed |