Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820957 | 0.84 | ALDH1A1 (0.46) | KMT2AALDH1A1GAATSHREPHX2 | |
| SCHEMBL15653564 | 0.81 | ALDH1A1 (0.54) | KMT2AL3MBTL1KDM1AMAOBALDH1A1 | |
| SCHEMBL3944464 | 0.80 | ALDH1A1 (0.69) | KMT2AL3MBTL1KDM1AMAOBDRD2 | |
| SCHEMBL6153463 | 0.80 | ALDH1A1 (0.69) | KMT2AL3MBTL1KDM1AMAOBDRD2 | |
| SCHEMBL3944460 | 0.80 | ALDH1A1 (0.69) | KMT2AL3MBTL1KDM1AMAOBDRD2 | |
| SCHEMBL3200309 | 0.78 | KMT2A (0.56) | KMT2AL3MBTL1KDM1AMAOBDRD2 | |
| SCHEMBL3200317 | 0.78 | KMT2A (0.56) | KMT2AL3MBTL1KDM1AMAOBDRD2 | |
| SCHEMBL15046662 | 0.77 | ALDH1A1 (0.61) | KMT2AALDH1A1GAATSHRCA1 | |
| SCHEMBL14817813 | 0.77 | BTK (0.46) | KMT2AL3MBTL1KDM1AMAOBDRD2 | |
| SCHEMBL5528389 | 0.76 | EPHX2 (0.60) | KMT2AL3MBTL1KDM1AMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048352-A2 | 2-CYANOPYRROLIDINES AND THEIR ANALOGUES AS DPP-IV INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | WO | disclosed |