Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784771 | 0.81 | KMT2A (0.58) | KMT2AKIF18ANPY1RMEN1RAB9A | |
| SCHEMBL2230607 | 0.80 | KMT2A (0.75) | KMT2AKIF18ANPY1RMEN1RAB9A | |
| SCHEMBL11591250 | 0.78 | HTR6 (0.61) | KMT2AKIF18ANPY1RMEN1RAB9A | |
| SCHEMBL9644188 | 0.77 | KIF18A (0.68) | KMT2AKIF18ANPY1RMEN1RAB9A | |
| SCHEMBL2041279 | 0.75 | KMT2A (1.00) | KMT2AKIF18AMEN1RAB9AHTR6 | |
| SCHEMBL11590219 | 0.75 | KMT2A (0.63) | KMT2AKIF18ANPY1RMEN1RAB9A | |
| SCHEMBL11490967 | 0.73 | KMT2A (0.56) | KMT2AKIF18ANPY1RMEN1RAB9A | |
| SCHEMBL8208093 | 0.72 | KMT2A (0.93) | KMT2AKIF18AMEN1RAB9AHTR6 | |
| SCHEMBL2903876 | 0.72 | KMT2A (0.58) | KMT2AKIF18ANPY1RMEN1RAB9A | |
| SCHEMBL27496823 | 0.72 | KMT2A (0.63) | KMT2AKIF18ANPY1RMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185265-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1185265-A1 | IL-8 RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000076501-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |
| EP-0991406-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-12-13 | — | — | EP | disclosed |
| EP-0991406-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998032439-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-30 | — | — | WO | disclosed |