Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818277 | 0.89 | SRD5A1 (0.41) | AHRCA12CA9CA2SRD5A1 | |
| SCHEMBL13692384 | 0.87 | NOTUM (0.38) | AHRCA12CA9CA2SRD5A1 | |
| SCHEMBL13689265 | 0.83 | CA12 (0.35) | AHRCA12CA9CA2SRD5A1 | |
| SCHEMBL13687525 | 0.82 | MEN1 (0.38) | AHRCA12CA9CA2SRD5A1 | |
| SCHEMBL14267965 | 0.74 | AHR (0.38) | AHRCMA1HTTMEN1KMT2A | |
| SCHEMBL8626958 | 0.73 | AHR (0.38) | AHRCMA1HTTMAOBMETAP1 | |
| SCHEMBL14864585 | 0.69 | NOTUM (0.36) | CA12CA9NOTUMHTTMEN1 | |
| SCHEMBL8817067 | 0.68 | AHR (0.58) | AHRCA2MAOBMAOAMETAP1 | |
| SCHEMBL11809222 | 0.67 | POLB (0.46) | SRD5A1SRD5A2NOTUMHSP90AA1MEN1 | |
| SCHEMBL9058392 | 0.66 | MTNR1A (0.44) | CA12CA9CA2NOTUMMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |