Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412110 | 0.86 | ALDH1A1 (0.71) | RAB9AGAATLR7MAPTLMNA | |
| SCHEMBL1249544 | 0.85 | RAB9A (0.66) | RAB9AGAATLR7MAPTLMNA | |
| SCHEMBL13078466 | 0.85 | RAB9A (0.70) | RAB9AGAATLR7MAPTLMNA | |
| Hydrochloric Acid SCHEMBL6821165 | 0.85 | ALDH1A1 (0.69) | RAB9AGAATLR7MAPTLMNA | |
| SCHEMBL6201061 | 0.85 | ALDH1A1 (0.73) | RAB9AGAATLR7TDP1KDM4E | |
| SCHEMBL168291 | 0.84 | TDP1 (0.67) | RAB9AGAATLR7MAPTLMNA | |
| SCHEMBL4735788 | 0.84 | HPGD (0.64) | RAB9AGAATLR7MAPTLMNA | |
| SCHEMBL2552765 | 0.81 | GAA (0.74) | RAB9AGAATLR7MAPTLMNA | |
| SCHEMBL13044108 | 0.81 | RAB9A (0.65) | RAB9AGAATLR7MAPTLMNA | |
| SCHEMBL3057919 | 0.81 | TLR7 (0.64) | RAB9AGAATLR7MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |