Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425136 | 0.92 | LMNA (0.63) | CYP2C19HIF1ALMNATYMPCYP2C9 | |
| SCHEMBL12917625 | 0.89 | CYP2C19 (0.58) | CYP2C19HIF1ALMNATYMPCYP2C9 | |
| SCHEMBL682135 | 0.87 | CYP2C19 (0.57) | CYP2C19HIF1ALMNATYMP | |
| SCHEMBL682177 | 0.86 | CYP2C19 (0.56) | CYP2C19HIF1ALMNATYMPCYP2C9 | |
| SCHEMBL11148896 | 0.86 | CYP2C19 (0.55) | CYP2C19HIF1ALMNATYMP | |
| SCHEMBL9561418 | 0.85 | CYP2C19 (0.47) | CYP2C19HIF1ALMNA | |
| SCHEMBL682403 | 0.85 | CYP2C19 (0.55) | CYP2C19HIF1ALMNA | |
| SCHEMBL682336 | 0.84 | LMNA (0.52) | CYP2C19HIF1ALMNACYP2C9 | |
| SCHEMBL18084232 | 0.83 | LMNA (0.83) | CYP2C19HIF1ALMNA | |
| SCHEMBL12917628 | 0.82 | CYP2C19 (0.51) | CYP2C19HIF1ALMNATYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8535642-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2013-09-17 | — | — | US | disclosed |
| US-8535642-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2013-09-17 | — | — | US | disclosed |
| US-8535642-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2013-09-17 | — | — | US | disclosed |
| US-20120039815-A9 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-02-16 | — | — | US | disclosed |
| US-20120039815-A9 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-02-16 | — | — | US | disclosed |
| US-20110052504-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2011-03-03 | — | — | US | disclosed |
| US-20110052504-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2011-03-03 | — | — | US | disclosed |
| WO-2009106552-A2 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039815-A9 | CONTRAST AGENTS | C5, TXN, CBR3 | CYP2C19 3568/4885HIF1A 337/4885LMNA 1863/4885 |
| US-20110052504-A1 | CONTRAST AGENTS | C5, TXN, CBR3 | CYP2C19 3568/4885HIF1A 337/4885LMNA 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.