Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL10694585 | 0.79 | TAAR1 (0.65) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL29706272 | 0.78 | TAAR1 (0.71) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL1222973 | 0.78 | TAAR1 (0.71) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL6594440 | 0.77 | HSPA5 (0.54) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL29706378 | 0.76 | TAAR1 (0.68) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL23852714 | 0.75 | TAAR1 (0.50) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL6944890 | 0.75 | TAAR1 (0.60) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL51747 | 0.75 | HTR1A (0.64) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL30595395 | 0.75 | HTR1A (0.64) | TAAR1HSPA5HTR1AMPOCYP2D6 | |
| SCHEMBL4967651 | 0.74 | TAAR1 (0.65) | TAAR1HSPA5HTR1AMPOCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737409-B2 | FOR CANCER THERAPY | HOFFMANN-LA ROCHE INC. | 2004-05-18 | — | — | US | disclosed |
| US-20030055002-A1 | Dolastatin 10 derivatives | HOFFMANN-LA ROCHE INC. | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055002-A1 | Dolastatin 10 derivatives | DAD1, DDOST, NPC1 | TAAR1 4852/4885HSPA5 3364/4885HTR1A 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.