Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821788 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6172110 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6172119 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27176728 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL12036067 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6822176 | 0.80 | MIF (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6822173 | 0.80 | MIF (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6818529 | 0.80 | MIF (0.54) | MAPTKDM4ECA1CA2LMNA | |
| SCHEMBL6818532 | 0.80 | MIF (0.54) | MAPTKDM4ECA1CA2LMNA | |
| Hydrochloric Acid SCHEMBL6822179 | 0.78 | MIF (0.53) | MAPTKDM4ECA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |