Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822176 | 1.00 | MIF (0.39) | MIFBACE1KDM1AALDH1A1KDM1B | |
| SCHEMBL6818532 | 0.85 | MIF (0.54) | MIFKDM4EMAPT | |
| SCHEMBL6818529 | 0.85 | MIF (0.54) | MIFKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6822179 | 0.84 | MIF (0.53) | MIFKDM4EMAPT | |
| SCHEMBL6821788 | 0.80 | ALDH1A1 (0.46) | KDM1AALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6821789 | 0.80 | ALDH1A1 (0.46) | KDM1AALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4929765 | 0.79 | MIF (0.56) | MIFKDM4EMAPT | |
| SCHEMBL4929762 | 0.79 | MIF (0.56) | MIFKDM4EMAPT | |
| SCHEMBL22046677 | 0.76 | HDAC3 (0.50) | MIFALDH1A1MEN1KMT2AGPR183 | |
| SCHEMBL30310600 | 0.76 | HDAC3 (0.50) | MIFALDH1A1MEN1KMT2AGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |