Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6966911 | 0.94 | TRPV1 (0.74) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL9080237 | 0.91 | MEN1 (0.83) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL7763386 | 0.89 | MEN1 (0.86) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL8697144 | 0.87 | TRPV1 (0.71) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL3435489 | 0.86 | TRPV1 (0.84) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL2942358 | 0.84 | MEN1 (0.96) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL17117495 | 0.83 | CA1 (0.76) | TRPV1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8699067 | 0.82 | TRPV1 (0.78) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL26393850 | 0.82 | TRPV1 (1.00) | TRPV1MEN1KMT2ALMNAGAA | |
| SCHEMBL28732580 | 0.82 | ALDH1A1 (0.92) | TRPV1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050646-A1 | 1, 2, 5-THIADIAZOLIDIN-3-ONE 1, 1 DIOXIDE DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PTP1B | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | WO | disclosed |