Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818800 | 0.88 | MAPT (0.51) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL6818234 | 0.88 | MAPT (0.54) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL6818655 | 0.86 | NPC1 (0.59) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL6818276 | 0.85 | MAPT (0.57) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL22619918 | 0.84 | RAB9A (0.67) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL7072562 | 0.83 | MAPT (0.53) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL6818513 | 0.81 | MAPT (0.54) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL6818861 | 0.80 | CNR2 (0.52) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL6818280 | 0.79 | CNR2 (0.66) | KDM4ENPC1MAPTTHRBALDH1A1 | |
| SCHEMBL6819659 | 0.78 | CNR2 (0.51) | KDM4ENPC1MAPTTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |