Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821883 | 0.86 | KDM4E (0.55) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL6818450 | 0.86 | ALDH1A1 (0.51) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL6821687 | 0.85 | NPC1 (0.57) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL6818780 | 0.83 | ALDH1A1 (0.55) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL6835889 | 0.81 | HSD17B10 (0.58) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1178011 | 0.81 | RAB9A (0.69) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL31039820 | 0.81 | RAB9A (0.69) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL6818638 | 0.79 | KDM4E (0.50) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL6815937 | 0.77 | ALDH1A1 (0.59) | NPC1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL6817821 | 0.77 | NPC1 (0.55) | NPC1KDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | NPC1 3778/4885KDM4E 1240/4885ALDH1A1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.