Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821991 | 0.83 | GPR119 (0.36) | SPHK1MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL6719414 | 0.81 | MEN1 (0.39) | SPHK1FKBP1AMEN1POLBKMT2A | |
| SCHEMBL14338696 | 0.80 | SPHK1 (0.42) | SPHK1SIGMAR1 | |
| SCHEMBL14350826 | 0.80 | SPHK1 (0.42) | SPHK1SIGMAR1 | |
| SCHEMBL6924329 | 0.80 | SPHK1 (0.42) | SPHK1SIGMAR1 | |
| SCHEMBL2081892 | 0.78 | SPHK1 (0.41) | SPHK1MEN1KMT2A | |
| SCHEMBL2081890 | 0.78 | SPHK1 (0.41) | SPHK1MEN1KMT2A | |
| SCHEMBL3612306 | 0.77 | SPHK1 (0.40) | SPHK1 | |
| SCHEMBL3612312 | 0.77 | SPHK1 (0.40) | SPHK1 | |
| SCHEMBL2079206 | 0.77 | SLC6A2 (0.40) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089915-A1 | PIPERAZINE DERIVATIVE RENIN INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |