Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822079 | 0.91 | GAA (0.39) | ADORA1HSD17B10USP2HPGDSMN1; SMN2 | |
| SCHEMBL6822552 | 0.91 | ADORA1 (0.40) | ADORA1SMN1; SMN2MAPTKMT2AADORA2A | |
| SCHEMBL6822496 | 0.89 | ADORA1 (0.42) | ADORA1MAPTADORA2AKHK | |
| SCHEMBL6822588 | 0.87 | ADORA1 (0.41) | ADORA1HSD17B10USP2SMN1; SMN2MAPK1 | |
| SCHEMBL6822109 | 0.86 | ADORA1 (0.41) | ADORA1SMN1; SMN2ALDH1A1MAPTADORA2A | |
| SCHEMBL6822056 | 0.86 | KHK (0.43) | ADORA1MAPTKMT2AIGF1RKHK | |
| SCHEMBL6822057 | 0.86 | ADORA1 (0.41) | ADORA1HSD17B10USP2SMN1; SMN2MAPK1 | |
| SCHEMBL6818374 | 0.85 | BRD4 (0.39) | ADORA1HSD17B10USP2ALDH1A1ADORA2A | |
| SCHEMBL6821993 | 0.85 | KHK (0.41) | ADORA1HSD17B10HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL6822097 | 0.85 | ADORA1 (0.39) | ADORA1MAPK1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | ADRB1, ADRA1D, ADRB3 | ADORA1 22/4885HSD17B10 962/4885USP2 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.