SCHEMBL6822145

SCHEMBL6822145

CCCCN(CC(=O)OCC)C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
CTSS P25774 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8230752 0.81 CYP1A2 (0.40) CTSKCYP1A2CYP2C9CYP2C19HTT
SCHEMBL7323221 0.81 CYP1A2 (0.45) CTSKCYP1A2CYP2C9CYP2C19HTT
SCHEMBL6825598 0.80 F7 (0.40) CTSKCYP1A2CYP2C9CYP2C19HTT
SCHEMBL8719939 0.80 CYP1A2 (0.44) CTSKCYP1A2CYP2C9CYP2C19HTT
SCHEMBL8140170 0.78 CA1 (0.40) CTSKCTSSCA1CA2CA7
Hydrochloric Acid SCHEMBL6825189 0.75 DPP4 (0.42) CYP1A2CA1CA2
SCHEMBL19981637 0.73 CTSK (0.48) CTSKCTSSCA1CA2CA7
SCHEMBL21974625 0.73 CYP1A2 (0.52) CTSKCYP1A2CYP2C9CYP2C19HTT
SCHEMBL28058637 0.73 CYP1A2 (0.52) CTSKCYP1A2CYP2C9CYP2C19HTT
SCHEMBL6825972 0.73 CCKBR (0.48) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO disclosed