Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824733 | 0.96 | ADORA1 (0.43) | ADORA1ADORA2ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6822105 | 0.87 | ADORA1 (0.43) | ADORA1ADORA2AALDH1A1POLB | |
| SCHEMBL6822494 | 0.86 | ADORA1 (0.43) | ADORA1ALDH1A1POLB | |
| SCHEMBL6818544 | 0.86 | ADORA1 (0.46) | ADORA1SMN1; SMN2POLBKMT2A | |
| SCHEMBL6822104 | 0.84 | SMN1; SMN2 (0.42) | ADORA1PIN1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6818603 | 0.84 | SMN1; SMN2 (0.42) | ADORA1PIN1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6822341 | 0.84 | ADORA1 (0.42) | ADORA1ALDH1A1 | |
| SCHEMBL6824869 | 0.84 | ADORA1 (0.42) | ADORA1MAPK8MAPK9ALDH1A1POLB | |
| SCHEMBL6821915 | 0.83 | SMN1; SMN2 (0.41) | ADORA1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6822338 | 0.83 | MEN1 (0.49) | ADORA1ADORA2AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110763-A1 | Pyrazolopyridine compound and pharmaceutical use thereof | ADRB1, ADRA1D, ADRB3 | CNR1 534/4885CNR2 454/4885ADORA1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.