Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 3/20 | 0.45 |
| ▸ | PDE5A | O76074 | 3/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821797 | 0.89 | MAPT (0.47) | EGFRMAPTMAPK1HCAR2PDE3B | |
| SCHEMBL6821801 | 0.84 | CYP1A2 (0.45) | — | |
| SCHEMBL6821850 | 0.81 | DAO (0.48) | MAPTDAODHODH | |
| SCHEMBL4381378 | 0.80 | DAO (0.40) | DAORXRAKDM5B | |
| SCHEMBL3655981 | 0.76 | EGFR (0.77) | EGFRMAPTDAO | |
| SCHEMBL6821792 | 0.76 | CYP1A2 (0.43) | EGFRPNP | |
| SCHEMBL4427278 | 0.74 | PDE3B (0.40) | PDE3BPDE3ARXRARXRB | |
| SCHEMBL28228782 | 0.74 | MAPT (0.40) | MAPTHCAR2DAO | |
| SCHEMBL11362552 | 0.73 | MAPT (0.43) | MAPTMAPK1HCAR2PDE3BPDE3A | |
| SCHEMBL6818415 | 0.72 | DAO (0.47) | MAPTDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |