Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818415 | 0.89 | DAO (0.47) | DAOMEN1MAPTKMT2AACP3 | |
| SCHEMBL6821880 | 0.84 | SRD5A2 (0.48) | DAODHODH | |
| SCHEMBL6821801 | 0.81 | CYP1A2 (0.45) | MEN1KMT2A | |
| SCHEMBL6822381 | 0.81 | EGFR (0.49) | DAODHODHMAPT | |
| SCHEMBL4381378 | 0.76 | DAO (0.40) | DAO | |
| SCHEMBL28228782 | 0.74 | MAPT (0.40) | DAONR4A2MAPT | |
| SCHEMBL8499067 | 0.74 | NR3C2 (0.50) | MEN1MAPTKMT2A | |
| SCHEMBL6821810 | 0.73 | DAO (0.41) | DAOMMP1MMP12PPARGPPARA | |
| SCHEMBL4430631 | 0.72 | ACP3 (0.42) | DAOMEN1KMT2AACP3 | |
| SCHEMBL4427278 | 0.72 | PDE3B (0.40) | FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |