Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 4/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822381 | 0.89 | EGFR (0.49) | MAPTMAPK1EGFRPDE3BPDE3A | |
| SCHEMBL6821792 | 0.84 | CYP1A2 (0.43) | EGFRPNPKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6818415 | 0.82 | DAO (0.47) | MAPTDAOKMT2AMEN1GAA | |
| SCHEMBL6821810 | 0.73 | DAO (0.41) | DAOALDH1A1KDM4E | |
| SCHEMBL11362552 | 0.73 | MAPT (0.43) | MAPTMAPK1PDE3BPDE3ADAO | |
| SCHEMBL6821801 | 0.72 | CYP1A2 (0.45) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6821850 | 0.70 | DAO (0.48) | MAPTDAOKMT2AMEN1 | |
| SCHEMBL9166149 | 0.69 | DPYD (0.60) | — | |
| SCHEMBL4381378 | 0.69 | DAO (0.40) | DAOALDH1A1 | |
| SCHEMBL3655981 | 0.69 | EGFR (0.77) | MAPTEGFRDAOKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |