SCHEMBL6822715 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	USP2	O75604	1/20	0.42

▸	SMN1; SMN2	Q16637	1/20	0.42

▸	GPR119	Q8TDV5	6/20	0.39

▸	DDB1	Q16531	1/20	0.35

▸	CRBN	Q96SW2	1/20	0.35

▸	PRKCA	P17252	1/20	0.35

▸	F13A1	P00488	2/20	0.35

▸	TGM2	P21980	2/20	0.35

▸	TGM1	P22735	2/20	0.35

▸	OPRD1	P41143	1/20	0.35

▸	OPRK1	P41145	1/20	0.35

▸	CHRM2	P08172	1/20	0.34

▸	CHRM4	P08173	1/20	0.34

▸	CHRM1	P11229	1/20	0.34

▸	CHRM3	P20309	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6823231	0.87	USP2 (0.41)	USP2SMN1; SMN2GPR119DDB1CRBN
SCHEMBL6823010	0.84	USP2 (0.44)	USP2SMN1; SMN2GPR119DDB1CRBN
SCHEMBL6823065	0.84	—	—
SCHEMBL6823567	0.78	USP2 (0.43)	USP2SMN1; SMN2GPR119DDB1CRBN
SCHEMBL6823515	0.75	USP2 (0.40)	USP2SMN1; SMN2GPR119OPRD1OPRK1
SCHEMBL1224512	0.74	USP2 (0.45)	USP2SMN1; SMN2DDB1CRBNF13A1
SCHEMBL31511515	0.74	USP2 (0.45)	USP2SMN1; SMN2DDB1CRBNF13A1
SCHEMBL371222	0.74	USP2 (0.45)	USP2SMN1; SMN2GPR119DDB1CRBN
SCHEMBL6823297	0.74	DDB1 (0.39)	USP2SMN1; SMN2GPR119DDB1CRBN
SCHEMBL2129847	0.73	USP2 (0.44)	USP2SMN1; SMN2DDB1CRBNF13A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004058763-A1	4(SPIROPIPERIDINYL)METHYL SUBSTITUTED PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY	MERCK & CO., INC. (US)	2004-07-15	—	—	WO	disclosed