Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824794 | 0.79 | GPR119 (0.49) | GPR119SMN1; SMN2IDO1 | |
| SCHEMBL7665691 | 0.78 | SSTR5 (0.52) | GPR119IDO1KMT2A | |
| SCHEMBL6822716 | 0.75 | USP2 (0.40) | DDB1CRBNGPR119USP2SMN1; SMN2 | |
| SCHEMBL6819442 | 0.74 | DDB1 (0.34) | DDB1CRBNGPR119IDO1KMT2A | |
| SCHEMBL6822715 | 0.74 | USP2 (0.42) | DDB1CRBNGPR119USP2SMN1; SMN2 | |
| SCHEMBL6823231 | 0.73 | USP2 (0.41) | DDB1CRBNGPR119USP2SMN1; SMN2 | |
| SCHEMBL31189134 | 0.72 | USP2 (0.47) | GPR119USP2SMN1; SMN2KMT2A | |
| SCHEMBL15166535 | 0.72 | USP2 (0.44) | GPR119USP2SMN1; SMN2IDO1KMT2A | |
| SCHEMBL3493829 | 0.72 | GPR119 (0.44) | DDB1CRBNGPR119USP2SMN1; SMN2 | |
| SCHEMBL21595331 | 0.71 | DDB1 (0.37) | DDB1CRBNGPR119USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058763-A1 | 4(SPIROPIPERIDINYL)METHYL SUBSTITUTED PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |