Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25905222 | 1.00 | MAP3K14 (0.44) | MAP3K14CRBNGLACYP19A1RAB9A | |
| SCHEMBL25905221 | 1.00 | MAP3K14 (0.44) | MAP3K14CRBNGLACYP19A1RAB9A | |
| SCHEMBL1536268 | 0.82 | MAP3K14 (0.41) | MAP3K14CRBNGLACYP19A1RAB9A | |
| SCHEMBL22394492 | 0.82 | MAP3K14 (0.41) | MAP3K14CRBNGLACYP19A1RAB9A | |
| Ammonia Solution, Strong SCHEMBL27873510 | 0.80 | MAP3K14 (0.40) | MAP3K14CRBNGLACYP19A1RAB9A | |
| SCHEMBL26177784 | 0.79 | CRBN (0.41) | MAP3K14CRBNRAB9ATDP1ALDH1A1 | |
| SCHEMBL755754 | 0.79 | MAP3K14 (0.39) | MAP3K14CRBNGLACYP19A1RAB9A | |
| SCHEMBL25467405 | 0.77 | CRBN (0.30) | CRBN | |
| SCHEMBL22623767 | 0.77 | CRBN (0.44) | CRBNTDP1ALDH1A1TSHRDDB1 | |
| SCHEMBL25046231 | 0.77 | CRBN (0.44) | CRBNTDP1ALDH1A1TSHRDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187083-B1 | INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER | XEROX CORPORATION | 2001-02-13 | — | — | US | claimed |
| CN-119421882-A | FGFR2 inhibitor compounds | 伊莱利利公司 | 2025-02-11 | — | — | CN | disclosed |
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024052333-A1 | MULTIVALENT FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2024-03-14 | — | — | WO | disclosed |
| US-20240066138-A1 | ANTIBODY-DRUG CONJUGATES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | SHANGHAI RUOTUO BIOSCIENCES CO LTD (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-11834417-B2 | Compositions for the treatment of hypertension and/or fibrosis | VECTUS BIOSYSTEMS LIMITED (AU) | 2023-12-05 | — | — | US | disclosed |
| US-11834417-B2 | Compositions for the treatment of hypertension and/or fibrosis | VECTUS BIOSYSTEMS LIMITED (AU) | 2023-12-05 | — | — | US | disclosed |
| US-20230330248-A1 | ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-10-19 | — | — | US | disclosed |
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20070249770-A1 | Binder Resin Composition, Paste and Green Sheet | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-10-25 | — | — | US | disclosed |
| US-20070244096-A1 | Fused Bicyclic Nitrogen-Containing Heterocycles | JAPAN TOBACCO INC. (JP) | 2007-10-18 | — | — | US | disclosed |
| CN-100338139-C | Heat-decaying material, transfer sheet using same, and method for forming pattern | SEKISUI CHEMICAL CO LTD (JP) | 2007-09-19 | — | — | CN | disclosed |
| US-7265150-B1 | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders | GPI NIL HOLDINGS INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-20070185098-A1 | Inhibitors of protein kinases | LOCUS PHARMACEUTICALS, INC. (US) | 2007-08-09 | — | — | US | disclosed |
| US-7244727-B2 | Fused bicyclic nitrogen-containing heterocycles | JAPAN TOBACCO INC. (JP) | 2007-07-17 | — | — | US | disclosed |
| CN-1972995-A | Binder resin composition, paste, and green sheet | SEKISUI CHEMICAL CO LTD (JP) | 2007-05-30 | — | — | CN | disclosed |
| CN-1708555-A | Heat-decaying material, transfer sheet using same, and method for forming pattern | SEKISUI CHEMICAL CO LTD (JP) | 2005-12-14 | — | — | CN | disclosed |
| CN-1524104-A | Photoreactive composition | ��Ԩ��ѧ��ҵ��ʽ���� | 2004-08-25 | — | — | CN | disclosed |
| US-6187083-B1 | INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER | XEROX CORPORATION | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | CRBN, CRKL, ERBB3 | MAP3K14 1475/4885CRBN 1/4885GLA 3961/4885 |
| US-20230330248-A1 | ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE | STING1, CGAS, TLR9 | MAP3K14 1842/4885CRBN 714/4885GLA 2707/4885 |
| US-20240016942-A1 | STAT DEGRADERS AND USES THEREOF | STAT4, STAT1, STAT3 | MAP3K14 1416/4885CRBN 171/4885GLA 1055/4885 |
| US-20070244096-A1 | Fused Bicyclic Nitrogen-Containing Heterocycles | PC, HCCS, MYC | MAP3K14 1686/4885CRBN 719/4885GLA 2574/4885 |
| US-11834417-B2 | Compositions for the treatment of hypertension and/or fibrosis | TGFB1, REN, TGFB2 | MAP3K14 1319/4885CRBN 3368/4885GLA 1068/4885 |
| US-20240066138-A1 | ANTIBODY-DRUG CONJUGATES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | FCGR1A, FCGRT, FCGR2A | MAP3K14 2551/4885CRBN 822/4885GLA 727/4885 |
| US-20070185098-A1 | Inhibitors of protein kinases | MAP3K20, MAP3K1, MAP3K19 | MAP3K14 28/4885CRBN 1527/4885GLA 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.