Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389719 | 0.78 | GUSB (0.43) | KDM4ECYP3A4MAPTPARP1TNKS2 | |
| SCHEMBL17047970 | 0.78 | DCPS (0.43) | KDM4ECYP3A4MAPTPARP1TNKS2 | |
| Hydrochloric Acid SCHEMBL7218019 | 0.77 | GUSB (0.42) | KDM4ECYP3A4MAPTPARP1TNKS2 | |
| SCHEMBL7216427 | 0.73 | NPY5R (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL5061741 | 0.72 | LCK (0.42) | KDM4ECYP3A4MAPTPARP1TNKS2 | |
| SCHEMBL2252074 | 0.70 | ADORA2A (0.47) | KDM4ECYP3A4MAPTADORA2ANUDT1 | |
| SCHEMBL971895 | 0.69 | LMNA (0.62) | KDM4ECYP3A4MAPTADORA2ANUDT1 | |
| SCHEMBL27810976 | 0.67 | LMNA (0.61) | KDM4ECYP3A4MAPTADORA2ANUDT1 | |
| SCHEMBL28239158 | 0.67 | LMNA (0.61) | KDM4ECYP3A4MAPTADORA2ANUDT1 | |
| SCHEMBL29514776 | 0.67 | ESR1 (0.73) | KDM4ECYP3A4MAPTADORA2ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058764-A1 | 4-PHENYL-PYRIMIDO [4,5-B] INDOLE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-07-15 | — | — | WO | claimed |
| WO-2004058764-A1 | 4-PHENYL-PYRIMIDO [4,5-B] INDOLE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058764-A1 | 4-PHENYL-PYRIMIDO [4,5-B] INDOLE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-07-15 | — | — | WO | disclosed |