Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.66 |
| ▸ | MGAM | O43451 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | SI | P14410 | 3/20 | 0.66 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.66 |
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | BACE1 | P56817 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822937 | 1.00 | CYP19A1 (1.00) | CYP19A1PTPN1PDE4DMGAMGAA | |
| Albanin A SCHEMBL27013487 | 0.90 | CYP19A1 (0.82) | CYP19A1PTPN1PDE4DGAABCHE | |
| SCHEMBL27006394 | 0.90 | CYP19A1 (0.82) | CYP19A1PTPN1PDE4DMGAMGAA | |
| SCHEMBL29808859 | 0.84 | CYP19A1 (0.71) | CYP19A1PTPN1PDE4DMGAMGAA | |
| SCHEMBL29580242 | 0.82 | CYP19A1 (0.69) | CYP19A1PTPN1MGAMGAASI | |
| SCHEMBL28037283 | 0.82 | CYP19A1 (0.69) | CYP19A1PTPN1PDE4DMGAMGAA | |
| SCHEMBL29378056 | 0.81 | PTPN1 (0.86) | CYP19A1PTPN1PDE4DMGAMGAA | |
| SCHEMBL28142325 | 0.81 | PTPN1 (0.74) | CYP19A1PTPN1PDE4DBCHEACHE | |
| SCHEMBL30578162 | 0.81 | CYP19A1 (0.67) | CYP19A1PTPN1MGAMGAASI | |
| Cudraflavone C SCHEMBL26679530 | 0.80 | PDE4D (1.00) | CYP19A1PTPN1PDE4DMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737439-B2 | ACTIVE CANCER CHEMOPREVENTATIVE AND TREATING AGENTS IN MAMMALS, INCLUDING HUMANS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2004-05-18 | — | — | US | claimed |
| US-20030125377-A1 | Aromatase inhibitors from Broussonetia papyrifera | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS THE | 2003-07-03 | — | — | US | claimed |
| CN-119118979-A | Isopentenyl polyphenol compound, application and preparation method thereof | 暨南大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-117903099-A | Isopentenyl polyphenol compound, application and preparation method thereof | 暨南大学 | 2024-04-19 | — | — | CN | disclosed |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
| CN-107987047-B | Geranylflavone compound extracted from cortex Mori, and its preparation method and application | 成都普思生物科技股份有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-107987047-B | Geranylflavone compound extracted from cortex Mori, and its preparation method and application | 成都普思生物科技股份有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-109078047-A | Have the preparation and application of the active component of tyrosinase inhibitory action in the root bark of white mulberry | 泉州师范学院 | 2018-12-25 | — | — | CN | disclosed |
| US-6737439-B2 | ACTIVE CANCER CHEMOPREVENTATIVE AND TREATING AGENTS IN MAMMALS, INCLUDING HUMANS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2004-05-18 | — | — | US | disclosed |
| US-20030125377-A1 | Aromatase inhibitors from Broussonetia papyrifera | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS THE | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125377-A1 | Aromatase inhibitors from Broussonetia papyrifera | CYP19A1, HSD17B11, CYP17A1 | CYP19A1 1/4885PTPN1 2076/4885PDE4D 1069/4885 |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | THPO, SERPINB1, SERPINC1 | CYP19A1 1668/4885PTPN1 1318/4885PDE4D 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.