Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.52 |
| ▸ | FPR2 | P25090 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822861 | 0.89 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL3138733 | 0.85 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL3138980 | 0.84 | SCN9A (0.64) | SCN9AFPR2 | |
| SCHEMBL3129012 | 0.84 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL3138877 | 0.81 | SCN9A (0.50) | SCN9AFPR2MAPT | |
| SCHEMBL3129152 | 0.81 | SCN9A (0.48) | SCN9AFPR2MAPT | |
| SCHEMBL27586185 | 0.80 | SCN9A (0.50) | SCN9AFPR2 | |
| SCHEMBL3138353 | 0.79 | SCN9A (0.49) | SCN9AFPR2MAPT | |
| SCHEMBL3138347 | 0.79 | SCN9A (0.49) | SCN9AFPR2MAPT | |
| SCHEMBL3139930 | 0.77 | SCN9A (0.52) | SCN9AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111011-A2 | SYNTHESIS OF 2-ARYL PYRIMIDINE 4-CARBOXYLIC ACID AMIDES | EURO-CELTIQUE S.A. (LU) | 2004-12-23 | — | — | WO | claimed |
| WO-2004111011-A2 | SYNTHESIS OF 2-ARYL PYRIMIDINE 4-CARBOXYLIC ACID AMIDES | EURO-CELTIQUE S.A. (LU) | 2004-12-23 | — | — | WO | disclosed |