Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138733 | 0.90 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL6822861 | 0.87 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL3134549 | 0.86 | SCN9A (0.53) | SCN9AFPR2 | |
| SCHEMBL3129012 | 0.86 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL19072393 | 0.84 | SCN9A (0.70) | SCN9AFPR2 | |
| SCHEMBL6822958 | 0.84 | SCN9A (0.52) | SCN9AFPR2 | |
| SCHEMBL27586185 | 0.83 | SCN9A (0.50) | SCN9AFPR2 | |
| SCHEMBL3139930 | 0.81 | SCN9A (0.52) | SCN9AFPR2 | |
| SCHEMBL3138353 | 0.81 | SCN9A (0.49) | SCN9AFPR2 | |
| SCHEMBL3138347 | 0.81 | SCN9A (0.49) | SCN9AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265866-B1 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-07-21 | — | — | EP | claimed |
| US-6867210-B2 | Aryl substituted pyrimidines | EURO-CELTIQUE S.A. (LU) | 2005-03-15 | — | — | US | claimed |
| WO-2004111011-A2 | SYNTHESIS OF 2-ARYL PYRIMIDINE 4-CARBOXYLIC ACID AMIDES | EURO-CELTIQUE S.A. (LU) | 2004-12-23 | — | — | WO | claimed |
| US-20040192691-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | EURO-CELTIQUE S.A. | 2004-09-30 | — | — | US | claimed |
| CN-1422254-A | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | EURO CELTIQUE SA (LU) | 2003-06-04 | — | — | CN | claimed |
| EP-1265866-A2 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | Euro-Celtique S.A. (LU) | 2002-12-18 | — | — | EP | claimed |
| US-20020040025-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | PURDUE PHARMA L.P. | 2002-04-04 | — | — | US | claimed |
| WO-2001068612-A2 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2001-09-20 | — | — | WO | claimed |
| EP-3258925-B1 | METHODS AND COMPOSITIONS FOR DECREASING GASTRIC EMPTYING | PURDUE PHARMA LP (US) | 2023-03-29 | — | — | EP | disclosed |
| EP-3293184-B1 | PYRIMIDINE CARBOXAMIDES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2020-12-16 | — | — | EP | disclosed |
| US-10143696-B2 | Methods and compositions for decreasing gastric emptying | PURDUE PHARMA L.P. (US) | 2018-12-04 | — | — | US | disclosed |
| EP-2964639-B1 | PYRIMIDINE CARBOXAMIDES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2018-05-02 | — | — | EP | disclosed |
| EP-3258925-A1 | METHODS AND COMPOSITIONS FOR DECREASING GASTRIC EMPTYING | Purdue Pharma LP (US) | 2017-12-27 | — | — | EP | disclosed |
| US-20170340646-A1 | Methods and Compositions for Decreasing Gastric Emptying | PURDUE PHARMA L.P. | 2017-11-30 | — | — | US | disclosed |
| WO-2004111011-A2 | SYNTHESIS OF 2-ARYL PYRIMIDINE 4-CARBOXYLIC ACID AMIDES | EURO-CELTIQUE S.A. (LU) | 2004-12-23 | — | — | WO | disclosed |
| US-20040192691-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | EURO-CELTIQUE S.A. | 2004-09-30 | — | — | US | disclosed |
| CN-1422254-A | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | EURO CELTIQUE SA (LU) | 2003-06-04 | — | — | CN | disclosed |
| EP-1265866-A2 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | Euro-Celtique S.A. (LU) | 2002-12-18 | — | — | EP | disclosed |
| US-20020040025-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | PURDUE PHARMA L.P. | 2002-04-04 | — | — | US | disclosed |
| WO-2001068612-A2 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340646-A1 | Methods and Compositions for Decreasing Gastric Emptying | GIPR, SLC10A2, CCKBR | SCN9A 372/4885FPR2 697/4885 |
| US-20040192691-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | CACNA1S, KYNU, CACNA1C | SCN9A 1388/4885FPR2 656/4885 |
| US-10143696-B2 | Methods and compositions for decreasing gastric emptying | GIPR, SLC10A2, CCKBR | SCN9A 372/4885FPR2 697/4885 |
| US-20020040025-A1 | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | CACNA1S, KYNU, CACNA1C | SCN9A 1388/4885FPR2 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.