Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.52 |
| ▸ | FPR2 | P25090 | 7/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131656 | 0.88 | SCN9A (0.52) | SCN9AFPR2FFAR4MET | |
| SCHEMBL3138733 | 0.84 | SCN9A (0.55) | SCN9AFPR2IGFBP3 | |
| SCHEMBL3138980 | 0.81 | SCN9A (0.64) | SCN9AFPR2 | |
| SCHEMBL6822861 | 0.80 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL3129152 | 0.79 | SCN9A (0.48) | SCN9AFPR2 | |
| SCHEMBL3129012 | 0.79 | SCN9A (0.55) | SCN9AFPR2 | |
| SCHEMBL6324173 | 0.78 | SCN9A (0.50) | SCN9AFPR2 | |
| SCHEMBL27586185 | 0.78 | SCN9A (0.50) | SCN9AFPR2IGFBP3 | |
| SCHEMBL6822958 | 0.77 | SCN9A (0.52) | SCN9AFPR2 | |
| SCHEMBL29254684 | 0.74 | LTA4H (0.48) | SCN9AFPR2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265866-B1 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-07-21 | — | — | EP | claimed |