SCHEMBL68230

SCHEMBL68230

O=Cc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.49
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
LMNA P02545 2/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTR7 P34969 1/20 0.43
HTR2B P41595 1/20 0.43
MAOA P21397 2/20 0.42
MIF P14174 3/20 0.40
BCHE P06276 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29882364 1.00 PNMT (0.49) PNMTNPC1RAB9ALMNAMEN1
SCHEMBL27609605 0.91 PNMT (0.47) PNMTNPC1RAB9ALMNAMEN1
SCHEMBL8359461 0.85 PNMT (0.49) PNMTNPC1RAB9ALMNAMEN1
SCHEMBL6421463 0.84 PNMT (0.52) PNMTNPC1RAB9ALMNAHTR7
SCHEMBL3952483 0.84 PNMT (0.52) PNMTNPC1RAB9ALMNAHTR7
SCHEMBL31143104 0.82 LMNA (0.47) PNMTNPC1RAB9ALMNAMEN1
SCHEMBL28208189 0.81 HSP90AA1 (0.39) PNMTNPC1RAB9ALMNAMEN1
SCHEMBL2877998 0.81 PNMT (0.61) PNMTNPC1RAB9ALMNAHTR7
SCHEMBL499896 0.81 PNMT (0.49) PNMTNPC1RAB9ALMNAMEN1
SCHEMBL19973034 0.81 PNMT (0.49) PNMTNPC1RAB9ALMNAHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908982-A Alkyl zinc complex and preparation method and application thereof 阜阳师范大学 2024-11-08 CN claimed
CN-115461056-B Inhibitors of Lebaba-specific tyrosine phosphatase (LYP) 普渡研究基金会 2024-04-16 CN claimed
CN-115521195-B Preparation method of fluorene formaldehyde compound 上海如鲲新材料股份有限公司 2024-01-26 CN claimed
CN-117269400-A Analysis method for total aldehyde content in industrial ethylene 宝来利安德巴赛尔石化有限公司 2023-12-22 CN claimed
CN-111587403-B Composition for hard mask 东友精细化工有限公司 2023-09-19 CN claimed
CN-113045389-B Synthesis method of 9, 9-bis (methoxymethyl) fluorene 中国科学院化学研究所 2021-12-31 CN claimed
CN-113045389-A Synthesis method of 9, 9-bis (methoxymethyl) fluorene 中国科学院化学研究所 2021-06-29 CN claimed
CN-111587403-A Composition for hard mask 东友精细化工有限公司 2020-08-25 CN claimed
CN-110408023-A A kind of fluorenyl fluorescent polymer and preparation method thereof UNIV HARBIN ENG 2019-11-05 CN claimed
WO-2019164231-A1 COMPOSITION FOR HARD MASK 동우화인켐 주식회사 2019-08-29 WO claimed
EP-0538399-A4 1994-05-04 EP claimed
EP-0565631-A1 ANTI-VIRAL COMPOUNDS. MERRELL DOW PHARMA (US) 1993-10-20 EP claimed
EP-0538399-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO., LTD. (JP) 1993-04-28 EP claimed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 EP claimed
WO-1992012123-A1 ANTI-VIRAL COMPOUNDS MERRELL DOW PHARMACEUTICALS INC. (US) 1992-07-23 WO claimed
WO-1992000995-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO. LTD. (JP) 1992-01-23 WO claimed
US-4461906-A IMPROVING INTELLECTUAL CAPACITY HOFFMANN-LA ROCHE INC. (US) 1984-07-24 US claimed
US-4452807-A CENTRAL NERVOUS SYSTEM DISORDERS HOFFMANN-LA ROCHE INC. (US) 1984-06-05 US claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed