SCHEMBL6823124

SCHEMBL6823124

C=CCCN(CC(=O)OCc1ccccc1)[C@@H](C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX5 P09917 2/20 0.40
FAAH O00519 2/20 0.39
MMP9 P14780 1/20 0.39
SLC15A1 P46059 1/20 0.38
KMT2A Q03164 1/20 0.38
CDC25B P30305 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6077522 1.00 ALDH1A1 (0.41) ALDH1A1MAPK1L3MBTL1ALOX5FAAH
SCHEMBL6077517 1.00 ALDH1A1 (0.41) ALDH1A1MAPK1L3MBTL1ALOX5FAAH
SCHEMBL1357622 0.88 TP53 (0.41) ALDH1A1KMT2A
SCHEMBL27156506 0.88 TP53 (0.41) ALDH1A1KMT2A
SCHEMBL10126870 0.85 KMT2A (0.42) ALDH1A1ALOX5KMT2A
SCHEMBL18045294 0.85 KMT2A (0.42) ALDH1A1ALOX5KMT2A
SCHEMBL12344914 0.82 ALOX5 (0.41) ALOX5KMT2A
SCHEMBL13624815 0.82 ALOX5 (0.41) ALOX5KMT2A
SCHEMBL18076669 0.80 KMT2A (0.41) ALDH1A1ALOX5KMT2A
SCHEMBL6823126 0.75 ALDH1A1 (0.45) ALDH1A1MAPK1L3MBTL1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042788-A1 STAT6 COMPOUNDS GILEAD SCIENCES INC (US) 2026-02-12 US disclosed
EP-2661433-B1 INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) NOVARTIS AG (CH) 2017-08-16 EP disclosed
US-9085555-B2 Complement pathway modulators and uses thereof NOVARTIS AG (CH) 2015-07-21 US disclosed
EP-2661433-A1 INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) Novartis AG (CH) 2013-11-13 EP disclosed
US-20120295884-A1 Complement pathway modulators and uses thereof NOVARTIS AG (CH) 2012-11-22 US disclosed
WO-2012093101-A1 INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) NOVARTIS AG (CH) 2012-07-12 WO disclosed
WO-2004032834-A2 THROMBIN INHIBITORS MERCK & CO., INC. (US) 2004-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042788-A1 STAT6 COMPOUNDS STAT6, IL6ST, NFATC1 ALDH1A1 1587/4885MAPK1 250/4885L3MBTL1 1069/4885
US-20120295884-A1 Complement pathway modulators and uses thereof C5, C3AR1, C9 ALDH1A1 2495/4885MAPK1 692/4885L3MBTL1 4875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.