⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20743619 | 0.67 | LOXL2 (0.43) | — | |
| SCHEMBL25850985 | 0.66 | — | — | |
| SCHEMBL20712793 | 0.66 | — | — | |
| SCHEMBL30517328 | 0.62 | — | — | |
| SCHEMBL883790 | 0.62 | — | — | |
| SCHEMBL30202555 | 0.62 | — | — | |
| SCHEMBL22322736 | 0.62 | — | — | |
| SCHEMBL2012248 | 0.62 | — | — | |
| SCHEMBL128301 | 0.62 | — | — | |
| SCHEMBL276906 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660889-B2 | Compounds for treatment of cancer | CUREGENIX, INC. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-20190142827-A1 | COMPOUNDS FOR TREATMENT OF CANCER | CUREGENIX, INC. (CN) | 2019-05-16 | — | — | US | disclosed |
| US-10253027-B2 | Aryl lactam kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-09 | — | — | US | disclosed |
| WO-2004108707-A1 | PYRIDAZINIL QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | disclosed |