⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20712793 | 1.00 | — | — | |
| SCHEMBL847904 | 0.80 | — | — | |
| SCHEMBL30101444 | 0.80 | — | — | |
| SCHEMBL24360007 | 0.76 | — | — | |
| SCHEMBL27334982 | 0.76 | — | — | |
| SCHEMBL19738628 | 0.76 | LOXL2 (0.33) | — | |
| SCHEMBL311571 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2894723 | 0.74 | ADRB2 (0.38) | — | |
| SCHEMBL21263464 | 0.73 | RAB9A (0.36) | — | |
| SCHEMBL22912584 | 0.73 | CYP11B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242550-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER | GENENTECH, INC. | 2023-08-03 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20190040080-A1 | BIARYL KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-02-07 | — | — | US | disclosed |