Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823777 | 0.87 | HTR2A (0.45) | HTR2ARETSLC22A1PRCPHRH1 | |
| SCHEMBL7196338 | 0.86 | ANPEP (0.52) | HTR2ASLC22A1PRCPHRH1HTR2C | |
| SCHEMBL5263777 | 0.83 | TSHR (0.50) | TSHRHTTEP300 | |
| SCHEMBL1708540 | 0.82 | SLC6A2 (0.47) | HTR2ATSHRHTTHTR2C | |
| SCHEMBL15617162 | 0.82 | TDP1 (0.41) | HTR2ASLC22A1PRCPTSHRHTT | |
| SCHEMBL6865807 | 0.82 | DRD2 (0.39) | HTR2ATSHRHTTHTR2C | |
| SCHEMBL3753138 | 0.82 | RET (0.42) | HTR2ARET | |
| SCHEMBL16473206 | 0.81 | GRIN2B (0.39) | SLC22A1PRCPTSHRHTTEP300 | |
| SCHEMBL1870242 | 0.79 | HTR2A (0.53) | HTR2ARETPRCPHRH1HTR2C | |
| SCHEMBL6826968 | 0.78 | HTR2A (0.50) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10611786-B2 | Manganese (III) catalyzed C—H aminations | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190106448-A1 | MANGANESE (III) CATALYZED C--H AMINATIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-04-11 | — | — | US | disclosed |
| EP-1119543-B1 | N-ARALKYLAMINOTETRALINS AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR | ORTHO MCNEIL PHARM INC (US) | 2004-12-15 | — | — | EP | disclosed |
| CN-1329589-A | N-aralkylamino 1,2,3, 4-tetrahydronaphthalenes as ligands of neuropeptide YY5 receptor | ORTHO MCNEIL PHARM INC (US) | 2002-01-02 | — | — | CN | disclosed |
| EP-1119543-A1 | N-ARALKYLAMINOTETRALINS AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR | Ortho-McNeil Pharmaceutical, Inc. (US) | 2001-08-01 | — | — | EP | disclosed |
| US-6201025-B1 | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-03-13 | — | — | US | disclosed |
| WO-2000020376-A1 | N-ARALKYLAMINOTETRALINS AS LIGANDS FOR THE NEUROPEPTIDE Y Y5 RECEPTOR | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-04-13 | — | — | WO | disclosed |
| EP-0489547-B1 | A process for the preparation of a 3-alkylated indole, intermediates, and a process for the preparation of a derivative thereof | ZENECA LTD (GB) | 1998-07-29 | — | — | EP | disclosed |
| US-4049701-A | ANALGESICS, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-4001331-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001326-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3979434-A | ANALGESICS, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3976696-A | ANALGESIC, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976693-A | ANALGESIC, ANTIINFLAMMATORY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3957872-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937736-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |
| US-3931328-A | CARBURETOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10611786-B2 | Manganese (III) catalyzed C—H aminations | HLCS, NCL, NUDC | HTR2A 4060/4885RET 4387/4885SLC22A1 2301/4885 |
| US-20190106448-A1 | MANGANESE (III) CATALYZED C--H AMINATIONS | HLCS, NCL, NUDC | HTR2A 3468/4885RET 4152/4885SLC22A1 2965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.