Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.68 |
| ▸ | C1S | P09871 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | F2 | P00734 | 3/20 | 0.67 |
| ▸ | F10 | P00742 | 1/20 | 0.67 |
| ▸ | F12 | P00748 | 1/20 | 0.67 |
| ▸ | F7 | P08709 | 1/20 | 0.67 |
| ▸ | F3 | P13726 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15902206 | 0.85 | LMNA (0.52) | PRSS1PRSS2PRSS3C1SRECQL | |
| Benzamidine SCHEMBL27541129 | 0.84 | PRSS1 (0.53) | PRSS1PRSS2PRSS3C1SRECQL | |
| Benzamidine SCHEMBL27527245 | 0.84 | PRSS1 (0.94) | PRSS1PRSS2PRSS3C1SRECQL | |
| Hydrochloric Acid SCHEMBL5860266 | 0.83 | PRSS1 (0.54) | PRSS1PRSS2PRSS3C1SRECQL | |
| Benzamidine SCHEMBL9040332 | 0.82 | PRSS1 (1.00) | PRSS1PRSS2PRSS3C1SRECQL | |
| Benzamidine SCHEMBL596593 | 0.82 | PRSS1 (1.00) | PRSS1PRSS2PRSS3C1SRECQL | |
| Benzamidine SCHEMBL23067876 | 0.82 | F2 (1.00) | PRSS1PRSS2PRSS3C1SRECQL | |
| Benzamidine SCHEMBL9207 | 0.82 | — | — | |
| SCHEMBL18557033 | 0.82 | F2 (1.00) | PRSS1PRSS2PRSS3C1SRECQL | |
| Benzamidine SCHEMBL27781057 | 0.82 | F2 (1.00) | PRSS1PRSS2PRSS3C1SRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062609-A2 | PYRIMIDINE DERIVATIVES AS IL-8 RECEPTOR ANTAGONISTS | PHARMACOPEIA, INC. (US) | 2004-07-29 | — | — | WO | disclosed |