SCHEMBL15902206

SCHEMBL15902206

N#Cc1ccc(C(=N)N)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
PLAU P00749 2/20 0.52
MASP2 O00187 1/20 0.52
THPO P40225 1/20 0.52
IDO1 P14902 2/20 0.52
PRSS1 P07477 4/20 0.50
CA2 P00918 3/20 0.50
F2 P00734 3/20 0.50
PRSS3 P35030 2/20 0.50
CA1 P00915 2/20 0.50
PARP15 Q460N3 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PRSS2 P07478 1/20 0.50
C1S P09871 1/20 0.50
RECQL P46063 1/20 0.50
KMT2A Q03164 1/20 0.50
APEX1 P27695 1/20 0.50
PRMT1 Q99873 2/20 0.49
CARM1 Q86X55 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5860266 0.98 PRSS1 (0.54) LMNAPLAUMASP2THPOIDO1
Benzamidine SCHEMBL6823484 0.85 PRSS1 (0.68) LMNAIDO1PRSS1F2PRSS3
SCHEMBL8973401 0.80 ASIC3 (0.58) LMNAPLAUMASP2THPOPRSS1
SCHEMBL15902204 0.80 ASIC3 (0.63) PLAUPRSS1F2PARP15PARP10
SCHEMBL537030 0.79 LMNA (0.77) LMNAPLAUMASP2THPOPRSS1
Guanidine SCHEMBL9846366 0.79 CA1 (0.53) IDO1CA2CA1PARP15PARP10
SCHEMBL20000003 0.76 CA2 (0.50) LMNAIDO1CA2CA1PARP15
SCHEMBL5456049 0.76 LMNA (0.52) LMNAPLAUMASP2THPOPRSS1
SCHEMBL322070 0.76 PARP15 (0.78) CA2CA1PARP15PARP10PARP2
SCHEMBL20008083 0.76 CA2 (0.50) LMNAIDO1CA2CA1PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150506-A1 CURING AGENTS FOR FLUOROELASTOMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US disclosed
CN-117529520-A Fluoroelastomer compositions containing curative 杜邦特种产品美国有限公司 2024-02-06 CN disclosed
EP-4305096-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS Dupont Specialty Products USA, LLC (US) 2024-01-17 EP disclosed
WO-2022192006-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS DUPONT POLYMERS, INC. (US) 2022-09-15 WO disclosed
CN-109468659-A The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase 云南师范大学 2019-03-15 CN disclosed
CN-109456273-A The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase 云南师范大学 2019-03-12 CN disclosed
WO-2017105041-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2017-06-22 WO disclosed
US-20150214491-A1 NOVEL AROMATIC HETEROCYCLIC DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL SOLUTION, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-07-30 US disclosed
US-20150214491-A1 NOVEL AROMATIC HETEROCYCLIC DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL SOLUTION, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-07-30 US disclosed
US-8975314-B2 Triazine derivative and ultraviolet absorber FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-20140213703-A1 NEW TRIAZINE DERIVATIVE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2014-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150214491-A1 NOVEL AROMATIC HETEROCYCLIC DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL SOLUTION, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO2A1, SLCO1A2 LMNA 1514/4885PLAU 3302/4885MASP2 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.