Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.62 |
| ▸ | KDR | P35968 | 14/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128347 | 0.86 | SRC (0.63) | SRCKDREGFR | |
| SCHEMBL6830967 | 0.86 | SRC (0.67) | SRCKDREGFR | |
| Hydrochloric Acid SCHEMBL6823476 | 0.86 | SRC (0.62) | SRCKDREGFR | |
| SCHEMBL6829415 | 0.85 | SRC (0.60) | SRCKDREGFR | |
| SCHEMBL6829449 | 0.85 | SRC (0.60) | SRCKDREGFR | |
| SCHEMBL6819711 | 0.84 | SRC (0.72) | SRCKDREGFR | |
| SCHEMBL6922194 | 0.84 | SRC (0.75) | SRCKDREGFR | |
| SCHEMBL6823640 | 0.84 | EGFR (0.54) | SRCKDREGFR | |
| SCHEMBL3205180 | 0.82 | SRC (0.55) | SRCKDREGFR | |
| SCHEMBL6823586 | 0.81 | SRC (0.61) | SRCKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056812-A1 | 4- (PYRIDIN-4-YLAMINO) -QUINAZOLINE DERIVATIVES AS ANTI-TUMOR AGENTS | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |