Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.39 |
| ▸ | AKT1 | P31749 | 8/20 | 0.38 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.37 |
| ▸ | AKT2 | P31751 | 2/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6824605 | 0.99 | DPP4 (0.40) | DPP4DPP7AKT1AKT1S1DPP8 | |
| SCHEMBL21794988 | 0.91 | AKT1 (0.39) | DPP4DPP7AKT1AKT1S1DPP8 | |
| SCHEMBL6824742 | 0.90 | DPP7 (0.40) | DPP4DPP7AKT1AKT1S1DPP8 | |
| Histidine SCHEMBL29740915 | 0.82 | GRB2 (0.46) | — | |
| SCHEMBL21419830 | 0.80 | ARG1 (0.38) | AKT1AKT1S1HDAC8 | |
| SCHEMBL7831182 | 0.79 | DPP7 (0.41) | DPP4DPP7AKT1AKT1S1DPP8 | |
| SCHEMBL8200272 | 0.79 | DPP7 (0.41) | DPP4DPP7AKT1AKT1S1DPP8 | |
| SCHEMBL28871462 | 0.78 | ITGB3 (0.39) | DPP4DPP8DPP9 | |
| SCHEMBL28287442 | 0.78 | ITGB3 (0.39) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6164842 | 0.78 | DPP7 (0.41) | DPP4DPP7AKT1AKT1S1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004076433-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |