Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887813 | 0.81 | PTGER1 (0.61) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6919700 | 0.79 | MRGPRX4 (0.47) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6820830 | 0.76 | MRGPRX4 (0.46) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL5171831 | 0.75 | MRGPRX4 (0.59) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6885785 | 0.73 | PTGER1 (0.49) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6881308 | 0.73 | L3MBTL1 (0.48) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL15197126 | 0.73 | NPC1 (0.55) | MRGPRX4PTGER1SMPD1HDAC1HDAC8 | |
| SCHEMBL6823947 | 0.73 | MRGPRX4 (0.43) | MRGPRX4PTGER1LRRK2 | |
| SCHEMBL171841 | 0.72 | MRGPRX4 (0.68) | MRGPRX4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7365989 | 0.71 | NPC1 (0.64) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |