Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ADCY10 | Q96PN6 | 3/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823543 | 0.88 | MRGPRX4 (0.42) | MRGPRX4PTGER1BRD4FEN1LRRK2 | |
| SCHEMBL6916270 | 0.87 | MRGPRX4 (0.41) | MRGPRX4PTGER1BRD4FEN1LRRK2 | |
| SCHEMBL7068093 | 0.83 | RAF1 (0.45) | MRGPRX4BRD4 | |
| SCHEMBL6826342 | 0.80 | KMT2A (0.40) | ADCY10HSP90AA1HSP90AB1 | |
| SCHEMBL6824812 | 0.78 | CDK1 (0.39) | BRD4 | |
| SCHEMBL6824523 | 0.77 | CCNT1 (0.47) | MRGPRX4PTGER1BRD4LRRK2DHODH | |
| SCHEMBL5095747 | 0.75 | BACE1 (0.54) | PTGER1HSP90AA1HSP90AB1 | |
| SCHEMBL6823726 | 0.73 | MRGPRX4 (0.50) | MRGPRX4PTGER1LRRK2 | |
| SCHEMBL4282091 | 0.73 | AGPAT2 (0.53) | PTGER1ADCY10HSP90AA1HSP90AB1 | |
| SCHEMBL6919700 | 0.71 | MRGPRX4 (0.47) | MRGPRX4PTGER1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |