Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062607 | 0.82 | CYP1A2 (0.58) | KMT2APOLBGRM5HSD11B1ALDH1A1 | |
| SCHEMBL6826032 | 0.81 | P2RY12 (0.49) | POLBTSHRP2RY12CXCR3GRM5 | |
| SCHEMBL3309889 | 0.77 | KMT2A (0.70) | KMT2APOLBTSHRKDM4EALDH1A1 | |
| SCHEMBL11399275 | 0.75 | KMT2A (0.68) | KMT2APOLBTSHRCNR2KDM4E | |
| SCHEMBL31057148 | 0.75 | KMT2A (0.68) | KMT2APOLBTSHRCNR2KDM4E | |
| SCHEMBL17746092 | 0.75 | KMT2A (0.68) | KMT2APOLBTSHRKDM4EALDH1A1 | |
| SCHEMBL6919706 | 0.75 | CYP2C9 (0.45) | KMT2AP2RY12CXCR3GRM5HPGD | |
| SCHEMBL13648884 | 0.75 | CXCR3 (0.55) | CXCR3HSD11B1 | |
| SCHEMBL6826225 | 0.75 | HPGD (0.49) | KMT2ATSHRCXCR3HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL3976856 | 0.74 | CXCR3 (0.54) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074287-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | claimed |
| WO-2004074287-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |