Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 17/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823786 | 1.00 | UTS2R (0.70) | UTS2RLMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL5835295 | 0.90 | UTS2R (0.75) | UTS2RLMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL5835300 | 0.90 | UTS2R (0.75) | UTS2RLMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL6824514 | 0.90 | UTS2R (0.64) | UTS2RMAPK1 | |
| SCHEMBL6824508 | 0.90 | UTS2R (0.64) | UTS2RMAPK1 | |
| SCHEMBL6821079 | 0.90 | UTS2R (0.64) | UTS2RSMN1; SMN2MEN1ALOX15MAPK1 | |
| SCHEMBL6821074 | 0.90 | UTS2R (0.64) | UTS2RSMN1; SMN2MEN1ALOX15MAPK1 | |
| SCHEMBL6820293 | 0.90 | UTS2R (0.62) | UTS2RLMNA | |
| SCHEMBL6820300 | 0.90 | UTS2R (0.62) | UTS2RLMNA | |
| SCHEMBL8339703 | 0.89 | UTS2R (0.61) | UTS2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |