Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.46 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.46 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712075 | 0.86 | GAPDH (0.45) | GAPDHHSPA1AHSPA8MEN1KMT2A | |
| SCHEMBL4712011 | 0.84 | GAPDH (0.47) | GAPDHHSPA1AHSPA8MEN1KMT2A | |
| SCHEMBL6823827 | 0.84 | GAPDH (0.34) | GAPDHHSPA1AHSPA8 | |
| SCHEMBL4712095 | 0.82 | HSPA1A (0.47) | GAPDHHSPA1AHSPA8MEN1KMT2A | |
| SCHEMBL4715692 | 0.81 | HSPA1A (0.45) | GAPDHHSPA1AHSPA8MEN1KMT2A | |
| SCHEMBL4714393 | 0.81 | GAPDH (0.47) | GAPDHHSPA1AHSPA8MEN1KMT2A | |
| SCHEMBL4710922 | 0.81 | GAPDH (0.45) | GAPDHHSPA1AHSPA8MEN1KMT2A | |
| SCHEMBL4712640 | 0.81 | HSPA1A (0.43) | GAPDHHSPA1AHSPA8PTPN7 | |
| SCHEMBL4712017 | 0.81 | GAPDH (0.44) | GAPDHHSPA1AHSPA8MEN1KMT2A | |
| SCHEMBL4711422 | 0.79 | GAPDH (0.43) | GAPDHHSPA1AHSPA8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069840-A2 | PRODUCTION OF TETRAHYDROQUINOLINE BENZOFURANS | Grünenthal GmbH (DE) | 2004-08-19 | — | — | WO | disclosed |